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• Beta Glucan (gluten-free oat): Lowers cholesterol, improves blood sugar control, supports immune function, and acts as a prebiotic.
• Apple Fibre: Supports regular bowel movements, maintains healthy blood sugar levels, and promotes beneficial gut bacteria growth.
• Rice Bran: Rich in antioxidants, supports heart health, aids in blood sugar regulation, and provides insoluble fiber for digestive health.
• Chicory Root Fibre: High in inulin, improves digestion, aids in blood sugar control, and may reduce gut inflammation.
• Guar Fibre: Lowers cholesterol, regulates blood sugar, promotes fullness, and supports digestive health.
• Soluble Corn Fibre: Promotes beneficial gut bacteria growth, supports digestive health, and helps maintain healthy blood sugar levels.

• A-Amylase: Breaks down complex carbohydrates, aiding in starch digestion.
• Protease: Breaks down proteins, supporting proper digestion and absorption.
• Lipase: Breaks down fats, aiding in digestion and absorption of dietary fats.
• Cellulase: Breaks down cellulose, improving digestion of plant-based foods.
• Lactase: Breaks down lactose, reducing symptoms of lactose intolerance.

• Vitamin B6: Supports neurotransmitter production, protein metabolism, and immune system function.
• Vitamin B12: Essential for red blood cell formation, nervous system function, and DNA synthesis.
• Vitamin D: Supports calcium absorption, bone health, immune function, and may reduce gut inflammation.
• Calcium: Essential for strong bones and teeth, supports muscle function and nerve signaling.

Biomel contains the following bacteria which are supported by scientific research:

• Improved symptoms of irritable bowel syndrome. The efficacy of a synbiotic containing Bacillus coagulans in treatment of irritable bowel syndrome: a randomized placebo-controlled trial
• Reduced sleeplessness and depression in patients with diarrhea-predominant irritable bowel syndrome. Bacillus coagulans MTCC 5856 Supplementation in the Management of Diarrhea Predominant Irritable Bowel Syndrome: A Double Blind Randomized Placebo Controlled Pilot Clinical Study
• Improved the gut microbiota of irritable bowel syndrome patients. Efficacy and Safety of Bacillus coagulans LBSC in Irritable Bowel Syndrome
• Improved irritable bowel syndrome symptoms in adults. Randomized Clinical Trial: The Effect of Probiotic Bacillus coagulans Unique IS2 vs. Placebo on the Symptoms Management of Irritable Bowel Syndrome in Adults

• Improved symptoms in women with irritable bowel syndrome. Efficacy of an Encapsulated Probiotic Bifidobacterium infantis 35,624 in Women with Irritable Bowel Syndrome

• Improved symptoms and quality of life in patients with irritable bowel syndrome. Randomized Clinical Trial: Bifidobacterium bifidum MIMBb75 Significantly Alleviates Irritable Bowel Syndrome and Improves Quality of Life—A Double-Blind, Placebo-Controlled Study
• Improved symptoms of irritable bowel syndrome. Effect of Administering a Multi-Species Probitic Mixture on the Change in Facial Microbiota and Symptoms of Irritable Bowel Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial
• Improved symptoms in patients with irritable bowel syndrome. Effect of a Composite Yogurt Enriched with Acacia Fiber and Bifidobacterium lactis on the Gut Microbiota of Patients with Irritable Bowel Syndrome

• Improved symptoms and markers of intestinal barrier function in patients with diarrhea-predominant irritable bowel syndrome. Clinical Response and Changes of Cytokines and Zonulin Levels in Patients with Diarrhoea-Predominant Irritable Bowel Syndrome Treated with Bifidobacterium longum ES1 for 8 or 12 Weeks: A Preliminary Report
• Improved visceral hypersensitivity and dysbiosis in an animal model of irritable bowel syndrome. Bifidobacterium longum Alleviates Irritable Bowel Syndrome-Related Visceral Hypersensitivity and Microbiota Dysbiosis via Paneth Cell Regulation
• Improved the social quality of life in patients with irritable bowel syndrome. Efficacy of Lactobacillus paracasei Ha-196 and Bifidobacterium lngum R0175 in Alleviating Symptoms of Irritable Bowel Syndrome (IBS): A Randomized, Placebo-Controlled Study
• Improved symptoms and markers of inflammation in an animal model of post-infectious irritable bowel syndrome. Effects of Probiotic Supplementation on Post-Infectious Irritable Bowel Syndrome in Rodent Model
• Improved symptoms in patients with diarrhea-predominant irritable bowel syndrome. The Effectiveness of Synbiotic Preparation Containing Lactobacillus and Bifidobacterium Probiotic Strains and Short Chain Fructooligosaccharides in Patients with Diarrhea Predominant Irritable Bowel Syndrome—A Randomized Double-Blind, Placebo-Controlled Study

• Improved abdominal pain and other symptoms in patients with irritable bowel syndrome. Efficacy and Safety of Lactobacillus acidophilus DDS-1 and Bifidobacterium lactis UABla-12 Improve Abdominal Pain Severity and Symptomology in Irritable Bowel Syndrome: Randomized Controlled Trial
• Improved symptoms in patients with irritable bowel syndrome. Efficacy of Lactobacillus acidophilus-SDC 2012, 2013 in Patients with Irritable Bowel Syndrome
• Improved abdominal pain and bloating in patients with diarrhea-predominant irritable bowel syndrome. The Effect of a Multispecies Probiotic on Microbiota Composition in a Clinical Trial of Patients with Diarrhea-Predominant Irritable Bowel Syndrome
• Improved symptoms in patients with diarrhea-predominant irritable bowel syndrome. The Effectiveness and Safety of Multi-Strain Probiotic Preparation in Patients with Diarrhea-Predominant Irritable Bowel Syndrome: A Randomized Controlled Study

• Did not significantly improve symptoms in patients with irritable bowel syndrome. The Effects of a Fermented Milk Containing Three Probiotic Bacteria in Patients with Irritable Bowel Syndrome—A Randomized, Double-Blind, Controlled Study
• Did not improve symptoms in patients with irritable bowel syndrome. Effects of Probiotic Fermented Milk on Symptoms and Intestinal Flora in Patients with Irritable Bowel Syndrome: A Randomized, Placebo-Controlled Trial
• Did not significantly impact the fecal microbiota of patients with irritable bowel syndrome. Effect of a Symbiotic Fermented Milk Containing Lactobacillus acidophilus La-5 and Bifidobacterium animalis ssp. lactis BB-12 on the Fecal Microbiota of Adults with Irritable Bowel Syndrome: A Randomized Double-Blind, Placebo-Controlled Trial

• Reduced inflammation in an ex vivo model of post-infectious irritable bowel syndrome. Lactobacillus casei DG and Its Postbiotic Reduce the Inflammatory Mucosal Response: An Ex-Vivo Organ Culture Model of Post-Infectious Irritable Bowel Syndrome
• Improved symptoms and markers of inflammation in an animal model of irritable bowel syndrome. Effect of Heat-Killed Lactobacillus casei DKGF7 on a Rat Model of Irritable Bowel Syndrome

• Was associated with weight loss in adults with obese tendencies. Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial

• Improved the social quality of life in patients with irritable bowel syndrome. Efficacy of Lactobacillus paracasei Ha-196 and Bifidobacterium lngum R0175 in Alleviating Symptoms of Irritable Bowel Syndrome (IBS): A Randomized, Placebo-Controlled Study
• Improved symptoms and markers of inflammation in an animal model of irritable bowel syndrome. Effect of Heat-Killed Lactobacillus casei DKGF7 on a Rat Model of Irritable Bowel Syndrome

• Improved symptoms in patients with irritable bowel syndrome. Clinical trial: Lactobacillus plantarum 299v (DSM 9843) improves symptoms of irritable bowel syndrome
• Improved symptoms in patients with irritable bowel syndrome. A controlled, double-blind, randomized study on the efficacy of Lactobacillus plantarum 299V in patients with irritable bowel syndrome

• Was effective in treating acute diarrhea in young children. Lactobacillus reuteri as a therapeutic agent in acute diarrhea in young children
• Improved symptoms and quality of life in patients with radiation-induced proctitis. Efficacy of synbiotics to reduce acute radiation proctitis symptoms and improve quality of life: a randomized, double-blind, placebo-controlled pilot trial

• Was effective in treating acute diarrhea in children. Lactobacillus rhamnosus GG administered in oral rehydration solution to children with acute diarrhea: a multicenter European trial
• Was effective in treating recurrent Clostridium difficile infection. Probiotics for recurrent Clostridium difficile disease
• Was effective in treating acute infectious diarrhea in infants and children. Treatment of acute infectious diarrhoea in infants and children with a mixture of three Lactobacillus rhamnosus strains—a randomized, double‐blind, placebo‐controlled trial
• Reduced the risk of atopic dermatitis when administered in early life. Probiotic administration in early life, atopy, and asthma: a meta-analysis of clinical trials

• Reduced the incidence of antibiotic-associated diarrhea. Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial
• Reduced the incidence of antibiotic-associated diarrhea. Effect of a fermented milk combining Lactobacillus acidophilus Cl1285 and Lactobacillus casei in the prevention of antibiotic-associated diarrhea: a randomized, double-blind, placebo-controlled trial

• Was effective in preventing antibiotic-associated diarrhea. Prevention of beta-lactam-associated diarrhea by Saccharomyces boulardii compared with placebo
• In combination with antibiotics was effective in treating Clostridium difficile disease. A randomized placebo-controlled trial of Saccharomyces boulardii in combination with standard antibiotics for Clostridium difficile disease
• Combined with high-dose vancomycin was effective in treating recurrent Clostridium difficile disease. The search for a better treatment for recurrent Clostridium difficile disease: use of high-dose vancomycin combined with Saccharomyces boulardii