RESEARCH STUDIES

Next generation gut health, backed by scientific research from leading experts.

At Biomel, every formulation is grounded in research and intentionally crafted using ingredients with purpose. We choose nutrients and functional compounds for their clinically researched benefits, ensuring they reflect the leading science that supports gut health, immunity and overall wellbeing.

CULTURES

Biomel’s multi-strain blend features clinically studied Bifidobacterium, Lactobacillus, and Bacillus species.

Live cultures


Live cultures in yoghurt or fermented milk improve lactose digestion of the product in individuals who have difficulty digesting lactose

Source: Great Britain Nutrition & Health Claims (NHC) Register

Bacillus coagulans

Role of Bacillus coagulans (Heyndrickxia coagulans)BCP92 in managing irritable bowel syndrome: A randomized, double-blind, multicenter, placebo-controlled clinical trial

Source: https://pubmed.ncbi.nlm.nih.gov/39093754/

 

Efficacy and safety of Bacillus coagulans LBSC in irritable bowel syndrome: A prospective, interventional, randomized, double-blind, placebo-controlled clinical study

Source: https://pubmed.ncbi.nlm.nih.gov/33545934/

 

Randomized clinical trial: the effect of probiotic Bacillus coagulans Unique IS2 vs. placebo on the symptoms management of irritable bowel syndrome in adults

Source: https://pubmed.ncbi.nlm.nih.gov/31434935/

Bifidobacterium bifidum


A randomised, double-blind, placebo-controlled trial of Bifidobacterium bifidum CCFM16 for manipulation of the gut microbiota and relief from chronic constipation

Source: https://pubmed.ncbi.nlm.nih.gov/35079761/

 

Heat-inactivated Bifidobacterium bifidum MIMBb75 (SYN-HI-001) in the treatment of irritable bowel syndrome: a multicentre, randomised, double-blind, placebo-controlled clinical trial

Source: https://pubmed.ncbi.nlm.nih.gov/32277872/

MACRONUTRIENTS

A precise blend of proteins, carbohydrates, and healthy fats fuels energy, supports muscle growth, and promotes overall vitality.

Protein


Protein contributes to a growth in muscle mass

Protein contributes to the maintenance of muscle mass

Protein contributes to the maintenance of normal bones

Protein is needed for normal growth and development of bone in children.

Source: Great Britain Nutrition & Health Claims (NHC) Register


Carbohydrates


Carbohydrates contribute to the recovery of normal muscle function (contraction) after highly intensive and/or long-lasting physical exercise leading to muscle fatigue and the depletion of glycogen stores in skeletal muscle

Source: Great Britain Nutrition & Health Claims (NHC) Register


Healthy Fats


ALA contributes to the maintenance of normal blood cholesterol levels

DHA contributes to maintenance of normal brain function

DHA and EPA contribute to the maintenance of normal blood pressure

DHA and EPA contribute to the normal function of the heart

Source: Great Britain Nutrition & Health Claims (NHC) Register

FIBRE

Biomel contains a blend of scientifically studied fibres—from apple and oat beta-glucans to chicory inulin and guar gum—that supports digestion, cholesterol balance, and healthy gut microbiota.

Apple fibre


Fruits and their impact on the gut microbiota, gut motility and constipation

Source: https://pubmed.ncbi.nlm.nih.gov/34505614/


Beta-glucans


Consumption of beta-glucans from oats or barley as part of a meal contributes to the reduction of the blood glucose rise after that meal

Oat beta-glucan has been shown to lower/reduce blood cholesterol. High cholesterol is a risk factor in the development of coronary heart disease

Source: Great Britain Nutrition & Health Claims (NHC) Register

Effect of dietary supplementation with oat β-glucan for 3 months in subjects with type 2 diabetes: A randomized, double-blind, controlled clinical trial

Source: https://www.sciencedirect.com/science/article/pii/S1756464620305351


Chicory inulin


Chicory inulin contributes to normal bowel function by increasing stool frequency

Source: Great Britain Nutrition & Health Claims (NHC) Register


Guar gum


Guar gum contributes to the maintenance of normal blood cholesterol levels

Source: Great Britain Nutrition & Health Claims (NHC) Register

Effect of Repeated Consumption of Partially Hydrolyzed Guar Gum on Fecal Characteristics and Gut Microbiota: A Randomized, Double-Blind, Placebo-Controlled, and Parallel-Group Clinical Trial

Source: https://pubmed.ncbi.nlm.nih.gov/31509971/

Randomized clinical study: Partially hydrolyzed guar gum (PHGG) versus placebo in the treatment of patients with irritable bowel syndrome

Source: https://pubmed.ncbi.nlm.nih.gov/26855665/

ENZYMES

Biomel is formulated with lactase and a clinically tested multienzyme complex to aid lactose digestion and support optimal nutrient absorption.

Lactase enzyme


Lactase enzyme improves lactose digestion in individuals who have difficulty digesting lactose

Source: Great Britain Nutrition & Health Claims (NHC) Register


Evaluation of the Safety and Efficacy of a Multienzyme Complex in Patients with Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Study

Source: https://pubmed.ncbi.nlm.nih.gov/30156436/

VITAMINS

Biomel contains a comprehensive blend of clinically supported nutrients—including calcium, magnesium, zinc, and vitamins B6, B12, and D—crafted to support energy, immunity, bone health, and cellular function.

Calcium


Calcium contributes to normal energy-yielding metabolism

Calcium contributes to normal neurotransmission

Calcium contributes to the normal function of digestive enzymes

Calcium has a role in the process of cell division and specialisation

Source: Great Britain Nutrition & Health Claims (NHC) Register


Magnesium


Magnesium contributes to a reduction of tiredness and fatigue

Magnesium contributes to electrolyte balance

Magnesium contributes to normal energy-yielding metabolism

Magnesium contributes to normal functioning of the nervous system

Magnesium contributes to normal muscle function

Magnesium contributes to normal protein synthesis

Magnesium contributes to normal psychological function

Magnesium contributes to the maintenance of normal bones

Magnesium contributes to the maintenance of normal teeth

Magnesium has a role in the process of cell division

Source: Great Britain Nutrition & Health Claims (NHC) Register


Vitamin B6


Vitamin B6 contributes to normal cysteine synthesis

Vitamin B6 contributes to normal energy-yielding metabolism

Vitamin B6 contributes to normal functioning of the nervous system

Vitamin B6 contributes to normal homocysteine metabolism

Vitamin B6 contributes to normal protein and glycogen metabolism

Vitamin B6 contributes to normal psychological function

Vitamin B6 contributes to normal red blood cell formation

Vitamin B6 contributes to the normal function of the immune system

Vitamin B6 contributes to the reduction of tiredness and fatigue

Vitamin B6 contributes to the regulation of hormonal activity

Source: Great Britain Nutrition & Health Claims (NHC) Register